When Adrienne Shapiro’s daughter Marissa was identified as having sickle cell disease, the doctors asserted she had not live till her first birthday. However, when Marissa were able to live past that benchmark, it didn’t mean the end of Adrienne’s worries. In fact, it turned out the start of many painful numerous years of blood transfusions and immunological disorders. When an improperly matched blood transfusion caused an intense reaction resulting in removing Marissa’s gallbladder and temporary kidney failure, she was can not receive further blood transfusions.
However, luckily for Marissa a job sponsored from the California Institute for Regenerative Medicine (CIRM), headed by Don Kohn, MD at UCLA, was creating a clinical trial. The aim of the project was ‘to remove bone marrow in the patient and correct the genetic defect in the blood-forming stem cells. Then those cells could be reintroduced to the patient to make a new, healthy blood system.’The success of this medical trial has provided wish to Adrienne that with the assistance regenerative medicine her daughter can lead a healthy and pain-free life.
The Stem Cell & Regenerative Medicine Center in the University of Wisconsin-Madison describes ‘Regenerative Medicine’ as ‘a new scientific and medical discipline dedicated to harnessing the effectiveness of stem cells and the body’s own regenerative capabilities to revive function to damaged cells, tissues and organs.’
Stem cells that are based in the umbilical cord blood of latest born children manage to renew and regenerate themselves. A stem cell, over the procedure for mitosis, can divide itself to either be a specialized cell just like a brain cell or muscle cell, or remain a stem cell. Fortunately they are capable to repair internal damage due to any kind of disease, disorder or trauma. Stem cell transplantation, stem cell grafting and regenerative medicine are among the methods these cells are used to cure disorders and illnesses.
Regenerative medicine includes a massive amount development, such as biochemistry, genetics, molecular biology and immunology. Scientists from these fields have been conducting studies on this domain and still have identified three strategies to using regenerative medicine. These are cellular therapies, tissue engineering and medical devices and artificial organs.
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