SINCE Wwii, medical science has progressed to some stage where competitive medications are for sale to treat the same ailment in several people. It’s not nearly brands (the industry trade issue) but generic drugs (the industry scientific issue). On this report, we shall go through the various factors that decide your selection of a specific drug.

Safety: These sub-criteria have to be considered within the criterion of safety:

* Acute therapeutic index: In the event the patient’s condition is acute, how effective is a particular drug even though they have certain side-effects so long as the acuteness of the condition is lowered? Example: narcotic pain-killers are amazing in healing pain but include the opportunity side-effect of addiction.

* Long-term safety: medication could be safe in short-term treatment, so how safe it can be in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but could have undesirable effects in the case of prolonged use.

* Drug-drug interaction risk: Medicine is chemicals, and several chemicals react to make a different chemical, which has an effect that could harm the individual or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to create a new condition that warrants separate treatment.

Drug-drug interaction risk is of two kinds:

· Pharmacokinetic: In this type of drug-drug interaction, two drugs, separate from the other, have certain effects using one or maybe more body processes (e.g., metabolism) that affects the performance of the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the action of a liver enzyme that Lexapro (escitalopram) is determined by due to the metabolism. This leads to an increase in the side-effects of Lexapro.

· Pharmacodynamic: Here, two or more drugs actually produce the same relation to the same organ, thus increasing the total, added effect. Example: Lexapro has certain side-effects including drowsiness and fatigue. Darvocet-N also acts similarly for the brain. Thus, the side-effects of both the medicine is more serious.

Tolerability: A medicine could be effective however, not tolerable by all patients. Example: Allergies to specific drugs in most people. Short-term and long-term tolerability need to be looked at. Efficacy: A medicine is not equally efficient at all patients. As an example, some patients with depression or panic disorders experience reduced escitalopram, but there are lots of that do not, who therefore need to be prescribed some other anti-depressant. The interest rate of beginning of therapeutic action is a crucial key to be regarded as too.

Cost: Cost does not mean the price tag on purchase of a specific medicine alone. It must also cover the price tag on treatments for a complication that could arise from using some other drug. Example: Within a one who insists on taking alcohol yet has to be treated for depression is normally administered an SSRI drug because these drugs don’t potentiate the end results of alcohol, whereas another gang of anti-depressants (including tricyclics) might cause a new symptom in such patients, which will demand a various and expensive treatment. Therefore, it’s safer to prescribe the more costly escitalopram rather than a cheaper tricyclic in these patients.

Simplicity of treatment: The best mode of administration is preferred. If you have an option between a shot and oral administration, the second is preferred if your efficacy of both the modes is comparable. Or, local application is preferred to the oral route where possible; e.g., antibiotic treatments for eye infections. Dosage and frequency of administration too are a key point to make a decision simple treatment.
For more information about medication just go to this popular web site: check it out