SINCE World war 2, medical science has progressed into a stage where competitive medications are around for treat precisely the same ailment in several people. It’s not just about brands (the industry trade issue) but generic drugs (the industry scientific issue). In this report, we shall look at the various factors that decide picking a a certain drug.

Safety: The following sub-criteria has to be considered beneath the criterion of safety:

* Acute therapeutic index: If your patient’s condition is acute, how effective is really a particular drug even when they have certain side-effects as long as the acuteness with the condition is lowered? Example: narcotic pain-killers are amazing in healing pain but come with the opportunity side-effect of addiction.

* Long-term safety: medication could possibly be safe in short-term treatment, so how safe it can be in long-term treatment? Example: antibiotics are acceptable in short-term treatment, but tend to have undesirable effects in case of prolonged use.

* Drug-drug interaction risk: Medicine is chemicals, and lots of chemicals reply to make a different chemical, which has an effect which could harm the person or aggravate his/her condition. Example: A tricyclic anti-depressant and alcohol interact to generate a new condition that warrants separate treatment.

Drug-drug interaction risk is of two kinds:

· Pharmacokinetic: In this kind of drug-drug interaction, two drugs, outside of each other, have certain effects using one or higher body processes (e.g., metabolism) that affects the performance with the other. Example: Darvocet-N (propoxyphene and acetaminophen) inhibits the act of a liver enzyme that Lexapro (escitalopram) is determined by for the metabolism. This makes an increase in the side-effects of Lexapro.

· Pharmacodynamic: Here, several drugs actually make the same influence on precisely the same organ, thus increasing the total, added effect. Example: Lexapro has certain side-effects such as drowsiness and fatigue. Darvocet-N also acts similarly around the brain. Thus, the side-effects of the medicine is more serious.

Tolerability: A medicine could possibly be effective although not tolerable by all patients. Example: Allergies to specific drugs in certain people. Short-term and long-term tolerability must be taken into consideration. Efficacy: A medicine isn’t equally efficient at all patients. For instance, some patients with depression or anxiety disorders experience rest from escitalopram, but there are many that do not, who therefore must be prescribed some other anti-depressant. The rate of start of therapeutic action is a step to be regarded as too.

Cost: Cost does not always mean the price of purchase of a particular medicine alone. It should also cover the price of treating a complication which could arise by using some other drug. Example: In the one who insists on taking alcohol and yet must be treated for depression is generally administered an SSRI drug because they drugs don’t potentiate the effects of alcohol, whereas another group of anti-depressants (such as tricyclics) could cause a brand new overuse injury in such patients, which may demand a different and expensive treatment. Therefore, it’s safer to prescribe the more costly escitalopram rather than a cheaper tricyclic such patients.

Simple treatment: The simplest mode of administration is preferred. If you have a selection between an injection and oral administration, aforementioned is preferred when the efficacy of the modes is the identical. Or, local application is chosen over the oral route where possible; e.g., antibiotic treating eye infections. Dosage and frequency of administration too are a key factor to determine simple treatment.
To learn more about medication check the best web site: visit here